Higher serum CCL17 may be a promising predictor of acute exacerbations in chronic hypersensitivity pneumonitis

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Higher serum CCL17 may be a promising predictor of acute exacerbations in chronic hypersensitivity pneumonitis

BACKGROUND Recent research has suggested that the Th1 and Th2 chemokine/cytokine axis contributes to the development of chronic hypersensitivity pneumonitis (HP). Acute exacerbations (AE) are significant factors in the prognosis of chronic HP. Little is known, however, about these biomarkers in association with AE in chronic HP patients. METHODS Fifty-six patients with chronic HP were evaluat...

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Chronic hypersensitivity pneumonitis

Hypersensitivity pneumonitis (HSP) is a common interstitial lung disease resulting from inhalation of a large variety of antigens by susceptible individuals. The disease is best classified as acute and chronic. Chronic HSP can be fibrosing or not. Fibrotic HSP has a large differential diagnosis and has a worse prognosis. The most common etiologies for HSP are reviewed. Diagnostic criteria are p...

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MAP3K1 May be a Promising Susceptibility Gene for Type 2 Diabetes Mellitus in an Iranian Population

Considering that MAPK (mitogen- activated protein kinase) signaling pathway has an important role in the progression of inflammatory cytokine secretion in type 2 diabetes mellitus (T2DM), we have recently investigated the reported genetic polymorphism from genome wide association study in MAP3K1 (mitogen-activated protein kinase kinase kinase 1) in diabetes as an important member of MAPK signal...

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Lung Cancer in Chronic Hypersensitivity Pneumonitis

Background: So far, the association of lung cancer with chronic hypersensitivity pneumonitis (CHP) has not been studied. Objective: We examined the prevalence and revealed clinical features of lung cancer in CHP. Methods: We retrospectively reviewed the medical records from 1994 through 2005 and identified 11 patients (15 lesions) with lung cancer among 104 patients with CHP. Their clinical fea...

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Lung cancer in chronic hypersensitivity pneumonitis.

BACKGROUND So far, the association of lung cancer with chronic hypersensitivity pneumonitis (CHP) has not been studied. OBJECTIVE We examined the prevalence and revealed clinical features of lung cancer in CHP. METHODS We retrospectively reviewed the medical records from 1994 through 2005 and identified 11 patients (15 lesions) with lung cancer among 104 patients with CHP. Their clinical fe...

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ژورنال

عنوان ژورنال: Respiratory Research

سال: 2013

ISSN: 1465-9921

DOI: 10.1186/1465-9921-14-57